Upon exposure to vaporized hydrogen peroxide, the color of the coated indicator strip progressively changes from blue toward pink along the strip. The progression of the blue to pink color change along the strip is visible through a window with marked REJECT and ACCEPT zones. The extent of the progression depends on exposure time, temperature, and amount of vaporized hydrogen peroxide.
The 3M Attest Vaporized Hydrogen Peroxide Tri-Metric Chemical Indicator 1348/1348E is a Type 4 indicator as categorized by ISO 11140-1:2014. The 3M Attest Tri-Metric 1348/1348E CI is the first and only CI in the FDAs newly-created multivariable indicator category for chemical vapor sterilization, as it independently verifies that the stated values of the three critical parameters of exposure time, temperature, and concentration of vaporized hydrogen peroxide have been met.